Fecal occult blood versus DNA testing: indirect comparison in a colorectal cancer screening population

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Fecal occult blood versus DNA testing: indirect comparison in a colorectal cancer screening population

BACKGROUND A multitarget stool DNA test (MSDT) that showed higher sensitivity but lower specificity than a fecal immunochemical test (FIT) for hemoglobin in one recent study from the US and Canada, is increasingly used for colorectal cancer (CRC) screening, despite its ~20-fold higher costs compared to FITs. We aimed to assess diagnostic performance of a quantitative FIT in an independent study...

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Screening for colorectal cancer with fecal occult blood testing.

153 SCREENING FOR COLORECTAL CANCER WITH FECAL OCCULT BLOOD TESTING AND COLONOSCOPY: CORRELATION OF CLINICAL DATA, SITE, SIZE AND DISEASE’S STAGE Iuliana Taraşi, Gabriela Florenţa Dumitrescu, Anca Indrei, P. Plămădeală, Anca Trifan, C. Stanciu, 1 Departament of Gastroenterology, „St. Spiridon” Emergency Clinical Hospital Iaşi 2 Department of Pathology, „Prof. Dr. N. Oblu” Emergency Clinical Hos...

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Fecal occult blood testing for colorectal cancer screening.

BACKGROUND Hemoccult II, a widely used guaiac test for fecal occult blood, has a low sensitivity for detecting colorectal neoplasms in asymptomatic patients at average risk. In such patients, the performance characteristics of screening tests developed to improve on Hemoccult II are not known. METHODS A set of three fecal occult-blood tests--Hemoccult II; Hemoccult II Sensa, a more sensitive ...

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Population colorectal cancer screening with fecal occult blood test.

Screening for early detection of colorectal cancer using fecal occult blood testing has been shown to be effective in reducing mortality from this disease. The largest Health Maintenance Organization in Israel initiated the use of Hemoccult Sensa in 1992 to evaluate the field performance of this test. All primary care physicians were invited to order home-based tests for their asymptomatic pati...

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ژورنال

عنوان ژورنال: Clinical Epidemiology

سال: 2017

ISSN: 1179-1349

DOI: 10.2147/clep.s136565